摘要
花色素是一类分布十分广泛的植物色素,在中草药材中也普遍存在。作者综述花色素抗癌试验的最新研究进展,包括抗氧化、抗DNA断裂,促使细胞分化、细胞凋亡,干扰细胞生长调节,抗血管生成功能等,以及它们的抗癌机理和构效关系,指出花色素药物研发的前景。
Anthocyanidin is a type of the plant pigments distributed very extensively, in traditional Chinese herbal products as well. In this review was introduced the recently progress in the anti-cancer trials of anthocyanidins, including the anti-oxidation, the prevention of DNA strand scission, stimulation of cell differentiation, induction of cell apoptosis, interference of regulation of cell proliferation, anti-angiogenic property etc, and the research of anti-cancer mechanisms of anthocyanidin and its structure-activity relationship, pointed the foreground of research and development of anti-cancer medicine.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2005年第15期1147-1150,共4页
China Journal of Chinese Materia Medica
基金
科学技术部科技中小企业技术创新基金(2004D40165)
关键词
花色素
花色素苷
抗癌机理
构效关系
anthocyanidin
anthocyanin
antitumor
structure-function relationship
