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骨髓检查在全血细胞减少中的诊断价值及320例病因分析 被引量:7

Evaluation of Bone Marrow Examinations in Differential Diagnosis for Patients with Pancytopenia and Causal Analysis of 320 cases
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摘要 目的:对比分析骨髓涂片与组织活检在全血细胞减少中的诊断价值以及引起全血细胞减少的常见病因。方法:选常规骨髓穿刺部位,用骨髓穿刺针先抽吸骨髓液行涂片,在隔2mm远处用骨髓活检针进针取骨髓组织活检;对比分析320例全血细胞减少患者的骨髓涂片与组织切片的结果。结果:骨髓活检切片与骨髓涂片增生程度一致者118例(36.9%),增生程度切片>涂片者41例(12.8%)。增生程度减低及重度减低者切片组152例(47.5%),骨髓涂片组193例(60.3%)。比较两者的骨髓增生程度,其差异存在统计学意义(P<0.01),骨髓活检对骨髓增生程度的判断优于涂片。两者结合起来更能反映骨髓细胞造血,提高诊断率。造血系统疾病是全血细胞减少的常见病因,也不能忽视非造血系统疾病所致的全血细胞减少。 Objective:To compare and evaluate the role of bone marrow smear and trephine biopsy in differential diagnosis of patients with pancytopenia and investigate the common causes of pancytopenia. Methods:Three hundred twenty cases were enrolled. Their bone marrow smear and biopsy section were analyzed, and compared with each other. Results: It was showed that the degree of cellularity in bone marrow biopsy was higher than that from the smear. Conclusion: Bone marrow biopsy section can offer better cellular structure compared with smear. Combination of bone marrow smear and biopsy was helpful for accurate diagnosis. However non-hemotological diseases should not be neglected.
出处 《内科急危重症杂志》 2005年第4期173-175,共3页 Journal of Critical Care In Internal Medicine
关键词 全血细胞减少 骨髓检查 临床分析 Pancytopenia Bone marrow examinations Clinical analysis
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