摘要
目的通过比较接受常规体外受精技术(IVF)及卵胞浆单精子注射技术(ICSI)治疗后妊娠的病例,分析临床资料、妊娠及产科结局,从而评估其安全性。方法对中山大学附属第一医院1998年1月至1999年12月接受体外受精-胚胎移植治疗后妊娠的533例临床资料进行回顾性分析。结果ICSI组受精率明显高于IVF组,IVF和ICSI两组早期胚胎发育情况、产科结局、围生情况及出生后婴儿的健康情况差异无显著性意义。结论与常规IVF相比,ICSI并不增加胎儿畸形率及新生儿并发症,但仍需要长期的大量的随访以排除可能的危险性。
Objective The aim of this study was to compare pregnancy characteristics and perinatal outcomes of intracytoplasmic sperm injection （ ICSI ） pregnancies with those of pregnancies obtained after in-vitro fertilization （IVF） , and thus evaluate respective safety. Methods A retrospective study was performed on 533 IVF and ICSI pregnancies between January 1996 and December 1999 in the First Affiliated Hospital of Sun Yet-Sen University of Medical Sciences.Results There were no significant differences in early embryonic development,obstetric outcomes,perinatal situation and neonatal health condition between IVF and ICSI. The fertilization rate of ICSI was significantly higher than that of IVF.Conclusions The ICSI did not increase risk of major malformation and neonatal complications comparedwith IVF; a consistent follow-up is still essential to exclude possible risks.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
2005年第8期475-477,共3页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
体外受精-胚胎移植
妊娠结局
卵胞浆单精子注射
In vitro fertilization and embryo transfer Pregnancy outcome Intracytoplasmic sperm injection
