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非小细胞肺癌癌旁组织DNA含量的流式细胞计量术分析

The Flow Cytometric Study on the Cellular DNA Content of Para-cancer Tissue in the Non-small Cell Lung Cancer (Non-SCLC)
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摘要 对33例非小细胞性肺癌患者癌分肺组织进行了DNA含量分析。结果表明:(1)癌旁组织异倍体检出率为41.7%;(2)癌中心灶为非整倍体或DI值为1.26~1.75时,癌细胞向周围组织侵袭能力最强;(3)癌细胞向周围组织侵袭过程中,其DNA倍体出现明显的不稳定性;(4)异倍体肿瘤向周围组织侵袭时存在明显的“跳跃现象”。 DNA content was measured on samples of paracancer tissue in 33 patients of non-SCLC. The results were as follows. (1) The positive rate of FCM is 41. 7% in the para-cancer tissue, (2) The disseminated capablity of aneuploidy cells or of near-triploidy DI value being 1. 26~ 1. 75 cells are the strongest in all cases of positive FCM. (3)The cancer nests tissue showed significant instability of ploiidy characteristecs when cancer cell disseminates. (4) The aneuploidy cancer cells indicates significant 'juinp behavior' as cancer cell disseminates.
出处 《江苏医药》 CAS CSCD 1995年第3期155-156,共2页 Jiangsu Medical Journal
关键词 肺肿瘤 癌旁组织 DNA 异倍体 流式细胞计量术 Flow cytometry Non-SCLC Para-cancer tissue DNA content
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参考文献1

  • 1周振英,林琳,戴亮,周平,张军妮,薛建平,黄富麟,郑秀立,陈嘉,高士娥,王岳祥.肿瘤高发区人群上消化道粘膜细胞的流式细胞术分析[J]江苏医药,1993(10).

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