摘要
芳香醛与３－甲基－１－苯基－５－吡唑啉酮固相缩合反应的研究李晚陆，麻洪，王永梅，孟继本（南开大学化学系，天津，３０００７１；兰州大学应用化学重点实验室）摘要研究了芳香醛与３－甲基－１－苯基－５－吡唑啉酮在室温固相、熔融状态及Ｌｅｗｉｓ酸催化下的缩合反...
In this paper,the condensation reactions of substituted benzaldehydes with 3 methyl-1-phenyl-5-pyrazolone at room temperature and with Lewis acid cataly;is in solid state and in melted state were investigated, and two products,4,4'-arylidene-bis-(3-methyl-1-phenyl-5-pyrazolone)2 and 4-arylidene-3-methyl-1-phenyl-5-pyrazolone l ,were prepared in high yields respectively.This solid state condensation, which had highly reactive selectivity and efficiency, might be a feasible synthetic method. In solution the bis-pyrazolone products 2 would be inverted into the mono-pyrazolone products 1 and pyrazolone,and the equilibrium of the interconversion between the two products 1 and 2 was reached gradually。In solid state the products 2 existed in enolic form, and could coordinated with copper ion easily.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1995年第12期1903-1906,共4页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
关键词
芳香醛
甲基
苯基
吡唑啉酮
缩合反应
Aromatic aldehyde,3-Methyl-1-pheny1-5-pyrazolone,Solid state condensation
