摘要
本实验证明人尿集落刺激因子（ＣＳＦ）能明显地提高受照射小鼠存活率，并延长存活时间。用微孔板有限稀释法培养粒细胞证明人尿ＣＳＦ能维持外用血粒细胞存活，且存活细胞数与ＣＳＦ浓度有密切关系。在含有人尿ＣＳＦ的条件下，骨髓粒－巨噬细胞存活数（ＣＦＵ－ＧＭ）在培养１２ｄ时较培养８ｄ者增多。
It was shown that colony stimulating factor (CSF) extracted fromhuman urine could increase survival rate obviously and prolonged survival time inirradiated mice. Using tissue culture mini-well plate by means of limiting dilutionmethod, it was shown that With CSF the mature granulocytes in peripheral bloodcould be kept survival and the counts of them were closely correlated with the concentrations of CSF. With CSF (200 u/ml), in the bone marrow culture the numbersof granulocyte-macrophage colony forming unit (CFU-GM) at the 12th day werelarger than that at the 8ib day.
出处
《辐射研究与辐射工艺学报》
CAS
CSCD
北大核心
1995年第2期91-94,共4页
Journal of Radiation Research and Radiation Processing
基金
江苏省科委资助
关键词
集落刺激因子
细胞存活
造血功能
小鼠
人尿
Colony stimulating factor(CSF)
Survival cells
Granulocyteemacrophage colony forming unit (CFU-GM). Haemopoietic function
