摘要
本文对16例受照者(12例肿瘤患者和4例皮肤搬痕患者)做了淋巴细胞SCE、细胞周期和M_1细胞的稳定性染色体畸变分析。结果表明,肿瘤患者SCE明显升高,在染色体中呈随机分布,无"热点"存在。同时显示细胞周期延迟现象。皮肤瘢痕患者未见到这些变化。事故组出现染色体畸变率明显增加,其中肿瘤患者更明显,并以稳定性畸变为主。
Zhou Zhenying
Cytogenetic changes in peripheral blood lymphocytes of 16 subjects (12 malignant tumor patients and 4 health persons) who were accidentally exposed to over-dose electron beam 110 days ago were studied. SCE, cell cycle and M_1 cell CA were analysed by stable aberrant technique.The result showed that the frequancy of SCE in tumor patients increased significantly and distribution of SCE was at random. No 'hot point' was observed. Analysis of M_1 cells and M_2 cells revealed that the incrsase of CA, CA -cell. Cu and Cs and statistical signifivance in all cases and that the cell cycle was significantly delayed, and Cs was predominant in the tumor patients.
出处
《遗传与疾病》
CSCD
北大核心
1989年第1期12-14,64,共3页
