摘要
用放射免疫法测定184例正常乳腺、良性乳腺疾病和乳腺癌患者血清催乳素浓度。结果显示:3组良性乳腺疾病血清催乳素含量无差别;乳腺癌及良性乳腺疾病均高于正常人;乳腺癌组明显高于良性乳腺疾病组;乳腺癌术后血中催乳素含量恢复正常。提示:循环血中催乳素异常升高可能是良性乳腺疾病发病原因之一,并与乳腺癌的发生、发展有密切关系。测定催乳素有助于乳腺良、恶性疾病的诊断及鉴别诊断,可作为乳腺癌预后的随访指标。
The clinical significance of serum prolactin(SP) determination is evaluated with radioimmunoassay in 184 normal women,patients with benign breast diseases and breast carcinomas.The results show,the SP of the 3 groups of benign breast diseases is not different; SP contents in patients with breast cancer and benign disease are significantly higher than that of normal control; those in patients with breast cancer is significantly higher than that in patients with benign breast disease.In the postoperated breast cancer patients the levels of SP return to normal The unusual elevation of SP may be one of the causes of benign breast disease and is closely related to the initiation and development of breast cancer.The SP determination may help to diagnose and differentiate the benign and the malignant,and to be an indicator for the prognosis of breast cancer in follow-up.
出处
《第三军医大学学报》
CAS
CSCD
北大核心
1989年第4期274-276,共3页
Journal of Third Military Medical University
关键词
催乳素
乳腺病
放射免疫测定
血清
breast diseases/DI
breast neoplasms/DI
prolactin/BL
radio-immunoassay/MT
prolactin determination
monitoring system
