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人冠状动脉的生物力学特性 Ⅲ.静态弹性模量与血管结构及其临床意义 被引量:5

Biomechanical Properties of Coronary Arteries in Human.Ⅲ.Static Elastic Moduli,Microstructure and Clinical Significance
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摘要 本文在生物软组织试验台上,对7例成人的左冠状动脉前室间支、旋支、右冠状动脉、胸廓内动脉以及大隐静脉进行二维载荷的力学试验,得到上述血管的增量弹性模量、容积弹性模量和压力-应变模量。血管的弹性模量随血压的增长而变大,胸廓内动脉的力学性质比大隐静脉更接近于冠状动脉,且有利于它在移植后保持较长期的畅通。动脉的C/E值大小能够反映动脉弹性的大小。本文还讨论了冠状动脉壁力学性质在动脉粥样硬化发病机理中的可能作用。 The anterior interventricular branch and the circumflex branch of the left coronary artery and the right coronary artery were excised from 7 autopsy adult subjects without heart diseases.The uniaxial loading test for the vascular specimens was completed,which was simultaneously finished in the internal thoracic artery(ITA) and the great saphenous vein (GSV) of the same subjects in order to compare with the coronary arteries.Young's moduli (dT/dλ) of the vessels increase with increasing tensile stress.Stress-strain relationships of the vessels were expressed by the exponential function.In comparison with GTV,the mechanical properties of ITA approach the coronary arteries.The relationships between-the microstructural components and the mechanical properties are discussed.It is assumed that the ratio of collagen elastin may be used as an index of the arterial elasticity.
出处 《第三军医大学学报》 CAS CSCD 北大核心 1989年第4期241-247,共7页 Journal of Third Military Medical University
基金 国家自然科学基金
关键词 生物力学 冠状动脉 应力-应变 一维 biomechanics aortocorouary bypass collagen elastin strain uniaxial
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