摘要1785年,英国医生William Withering发表“An account of the foxglove and some of itsmedical uses”成为洋地黄类药物进入临床的标志。狄戈辛作为其中之一种,应用最广泛。已是充血性心力衰竭的支柱性治疗手段。近年来,对其认识也逐步发展和深化。对于这种经常使用且毒副反应易于发生的药物,把握其药效学的重要意义至关重要。
1Roberto Bolognesi,Dimitri Tsialtas,Carlo Manca. Digitalis and heart failure: Does digitalis really produce beneficial effects through a positive inotropic action?[J] 1992,Cardiovascular Drugs and Therapy(5):459～464
2Philip A. Poole-Wilson,Killian Robinson. Digoxin—A redundant drug in congestive cardiac failure[J] 1989,Cardiovascular Drugs and Therapy(6):733～741
3Toshiaki Kumada,Chuichi Kawai. Can new inodilators displace digitalis in the therapy of congestive heart failure?[J] 1989,Cardiovascular Drugs and Therapy(6):751～755
