摘要
成人急性非淋巴细胞白血病５０例，作者采用ＨＡＤ方案诱导化疗，缓解后以ＨＡＤ、ＥＡ、ＭＡ或冉加ＡＡ方案巩固强化。结果完全缓解（ＣＲ）４３例，ＣＲ率８６．０％。初治３８例，ＣＲ３３例（８６．８％），复治１２例，ＣＲ１０例（８３．３％）。ＣＲ４３例中３３例（７６．７％）仅用１疗程即达ＣＲ。远期疗效仍在观察中。ＨＡＤ方案毒性低，能为患者接受。取得高缓解率的原因可能与高三尖杉酯碱和柔红霉素之间的协同作用有关。
ifty patients with acute nonlymphoblasticleukemias (ANLL) were treated with homoharring-tonine (HHT) , cytarabine and daunorubicin (HAD)regimen . Forty-three patients (86. 0%) achieved com-plete remission (CR). The CR rates in 38 previously un-treated patients and 12 previously treated patients were86. 8% and 83. 8% ,respectively . Thirty-threel43 (76.7%) patients achieved CR with one course of treatment.The toxicities related to HAD regimen were well tolerat-ed by all patients treated. It seems that HHT and DNRmight have synergistic effect in the treatment of ANLLpatients.
出处
《中华血液学杂志》
CAS
CSCD
北大核心
1995年第2期59-61,共3页
Chinese Journal of Hematology
基金
卫生部科学基金
