摘要
对５６例特发性真性性早熟女孩，用Ｂ超检查子宫和卵巢形态，并于同日抽血，用放射免疫法测定ＬＨ、ＦＳＨ和Ｅ＿２。结果显示卵巢容积与三种激素均不相关，但最大卵泡直径与ＬＨ、Ｅ＿２及卵巢总容积显著相关。直径≥４ｍｍ的卵泡呈现率随发育成熟度显著增加，并与子宫腔内膜线可辨率高度相关。Ⅲ期后有＞８ｍｍ的卵泡出现。子宫体容积与ＬＨ和Ｅ＿２均相关。提示卵巢和子宫形态是血ＬＨ和Ｅ＿２水平的组织影像学印迹，其中卵巢有≥４ｍｍ的卵泡（尤其＞８ｍｍ）伴宫腔内膜线可辨，结合垂体－性腺轴激素水平。
Observations on ovary and uterus by ultrasonography and measuring the serum level of LH, FSH and E-2 by radioimmunoassaywere done for 56 cases of girls with idiopathic true precocious puberty. The results showed that the ovary volumes did not correlateto the levels of LH , FSH and E-2,but the diameters of maximal follicles correlated to the levels of serum LH, E-2 and the ovary vol-umes. The frequency of follicles exceeding 4mm in diameter was significantly increasing with the pubescence stages and correlated tothe recognizable frequency of uterine endometrial shadows. The follicles exceeding 8mm in diameter did not appear until stage 3.Uterus volumes correlated to the levels of serum LH , E-2. The results suggest that the aspect of ovary and uterus in ultrasonographyCOuld serve as a print of histomorphological images for rising serum LH and E-2. The follicle 4mm or even 8mm in diameter accompa-nied by a definite endometrial shadow is the significant ultrasonographic evidence for diagnosis of true precocious puberty. To com-bine the ultrasonal display with the hormone levels of hypophysis-gonadol axis is helpful for differential diagnosis of precocious pu-berty.
出处
《中华内分泌代谢杂志》
CSCD
北大核心
1995年第1期22-24,共3页
Chinese Journal of Endocrinology and Metabolism
关键词
性早熟
LH
E2
子宫
卵巢
卵泡
FSH
血清
True precocious puberty LH E-2 Ovary Uterus Follicle Ultrasonography
