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肾移植患者存活五年以上76例临床研究 被引量:1

A clinical study of 76 kidney recipients surviving 5 years
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摘要 对肾移植后超过5年的141例,152例次患者的资料进行分析,人/肾5年存活率分别为53.9%/42.1%.环孢素A组明显优于硫唑嘌呤组(P<0.05),淋巴细胞毒试验值0~、5/~、10%~15%其5年肾存活率分别为52.4%、5.5%、18.1%,其中<5%者效果最佳,各组之间差异非常显著(P<0.01),对患者的术前准备、供肾选择、处理、免疫抑制剂应用、并发症的防治和长期随诊工作进行了讨论. The clinical data of 141 cases of kidney transplantation (152 grafts)surviving more than 5 years were reviewed.The 5-year survival rate of the recipient and of the graft was 53.9%(76/141)and 42.1%(64/152)respectively and both were higher in the CsA group than the azathioprine group(P<0. 05).As the lymphocytotoxity test was concerned, the 5-year survival rate with 0%~,5.0%~and 10.0%~15.0% was 52.4%, 25.5%and 18.1%respectively with much more long survivals in the 0%~5%group.The difference was conspicuous(P<0.01).The preoperative preparation,donor selection, immunosuppressant application and the prophylaxis and treatment of complications were discussed.
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 1995年第3期143-145,共3页 Chinese Journal of Urology
关键词 肾移植 环孢素 免疫学 Transplantation Kidney CyClosporins Follow-up studies
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参考文献2

  • 1谢桐,中华泌尿外科杂志,1992年,13卷,409页
  • 2谢桐,中华器官移植杂志,1992年,13卷,56页

同被引文献5

  • 1于立新,白喜文,王进义,罗永礼,徐健,潘光辉,马俊杰,付绍杰,邓文锋.15年肾移植的临床经验[J].中华泌尿外科杂志,1995,16(1):7-9. 被引量:5
  • 2Terasaki PI,Cho Y,Takemoto S,et al. Twenty- year follow-up on the effect of HLA matching on kidney transplant survival and prediction of future twenty- year survival. Transplant Proc, 1996;28(3) : 1144--5.
  • 3Kerman RH, Kimball PM, Lindholm, A, et al. Influence of HLA matching on rejections and short - and long - term primary cadaveric allograft survival. Transplantation, 1993; 56(5) : 1242-7.
  • 4McKenna RM, Lee KR, Cough JC, et al. Matching for private or public HLA epitopes reduces acute rejection episodes and improves two- year renal allograft function. Transplantation,1998;66(1) :38-43.
  • 5Slavis SA, Novick AC, Steinmuller DR, et al. Outcome of renal transplantation in patients with a functioning graft for 20 years or more. J Urol, 1990; 144(1) : 20 - 2.

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