2Carlos A, Rosane P, Osvaldo M, et al.Polymerase chain reaction on cerebrospinal fluid cells in suspected leptomeningeal involvement in childhood acute lymphoblastic leukemia: comparison to cytomorphological analysis.Diagn Mol Pathol, 2003, 12(3): 124-127.
3Stewart DJ, Keating MJ, Mccreclie KB, et al.Natural history of central nervous system acute leukemia in adults.Cancer, 1981, 47: 184-196.
4Carlos V, Maria RB, Clara DB.Uncommon patterns of presentation of leukemia.Hematol Oncol, 1999, 17: 11-29.
5Campana D, Pui CH.Detection of minimal residual di-sease in acute leukemia: methodologic advances and clinical significance.Blood, 1995, 85: 1416-1434.
7Darrell JC, Foon KA.Recent advances in flow cytometry: application to diagnosis of hematologic malignancy.Blood, 1997, 90(8): 2863-2892.
8de Haas V, Vergagen OJ, Kroes W, et al.Early detection of central nervous system relapse by polymerase chain reaction in children with B-precursor acute lymphoblas-tic leukemia.Ann Hematol, 2002, 81: 59-61.
1Ernest B, Marshalla L, Barrys C, et al. Williams Hematology [M].北京:人民卫生出版社,2001:1455-1465.
2Roy A, Bradburn M, Moorman AV, et al. Early response to induction is predictive of survival in children philadelphia chromosome positive acute lymphoblastic leukemia: results of the medical research council ALL 97 trial [ J ]. British Journal of Haematology, 2005,129:35-44.
3Schrappe M, Reiter A, Ludwig WD, et al. Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90 [J]. Blood,2000,95(11):3310-3322.
4Campana D, Pui CH. Detection of minimal residual disease in acute leukemia: methodologic advances and clinical significance [J]. Blood, 1995,85 : 1416.
5Panetta JC, Wall A, Pui CH, et al. Methotrexate intracellular disposition in acute lymphoblastic leukemia: A mathematical model of gamma-glutamyl hydrolase activity [J]. Clinical Cancer Research,2002,7(8):2423-2429.