摘要
目的供肝短缺是影响肝脏移植发展的主要因素之一,活体供肝是解决这一矛盾的重要措施,供者提供足够的肝脏是影响活体肝脏移植的重要因素。方法施行成人间双供体活体肝移植2例,1例由受者的两位姐姐分别提供左半肝作为供肝,另1例由受者母亲提供右半肝,由无心跳供者提供左半肝(采用劈裂方式,其另一部分肝脏同时为另一成人受者实施肝脏移植)作为供肝。结果术后供、受者肝功能均恢复良好。结论成人间双供肝活体肝脏移植可以为受者提供更大重量的肝脏,又可减少供者提供较多肝脏所带来的风险;双供肝一受者肝脏移植手术操作复杂。
Objective The growing gap between the number of patients waiting for transplantation and available organs has continued to be the number one issue facing the transplant community. The major limitation of adult-to-adult living donor liver transplantation (LDLT) is the adequacy of the graft size. But donor safety is the major concern in LDLT. Methods Two patients with end-stage liver disease were successfully performed adult-to-adult LDLT using dual grafts in our division. One patient's donors are left lobe and left lobe from his two old sisters , respectively. The other graft are right lobe from his 56 years-old mother and left lobe splitting from a cadaveric organ donor (the other part of split-liver transplants from the the cadaveric organ donor offer to another adult donor ). Results Both recipients and three donors display good graft function and normal triangularshape regeneration of their liver grafts after liver transplantation. There was neither a mortality nor a serious complications in the donors. Conclusion The critical issue of LDLT is donor morbidity. Dual grafts from two living donors can help to alleviate the problem of small-for-size grafts and yet secure the safety of the donor. But the complicated surgical technique give a great challenge for liver transplant surgeons.
出处
《中国普外基础与临床杂志》
CAS
2005年第4期399-402,共4页
Chinese Journal of Bases and Clinics In General Surgery
关键词
活体供肝
双供肝
成人间
活体供肝肝移植
劈裂式肝移植供体
Living donor Dual grafts Adult-to-Adult Living donor liver transplantation Split-liver transplant donor
