1Ruiz Gines JA,Lopez Ongil S,Gonzalez Rubio M,et al.Reactive oxygen species induce proliferation of bovine aortic endothelial cells[J].J Cardiovasc Pharmacol,2000,35(1):109～113.
2Lebuffe G,Schumacker PT,Shao ZH,et al.ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel[J].Am J Physiol Heart Circ Physiol,2003,284(1):299～308.
3Zhong-kai Wu,Matti R.Tarkka,Jussi Eloranta,et al.Effect of Ischemic Preconditioning on Myocardial Protection in Coronary Artery Bypass Graft Patients[J].Chest,2001,119:1 061～1 068.
4Vanden Hoek T,Becker LB,Shao Z,et al.Reactive oxygen species released from mitochondria during brief hypoxia induce preconditioning in cardiomyocytes[J].J Biol Chem,1998,273(29):18 092～18 098.
5Vanden Hoek T,Becker LB,Shao ZH,et al.Preconditioning in cardiomyocytes protects by attenuating oxidant stress at reperfusion[J].Circ Res,2000,86(5):541～548.
6Altug S,Demiryurek AT,Kane KA,et al.Evidence for the involvement of peroxynitrite in ischaemic preconditioning in rat isolated hearts[J].Br J Pharmacol,2000,130:125～131.
7Tang XL,Takano H,Rizvi A,et al.Oxidant species trigger late preconditioning against myocardial stunning in conscious rabbits[J].Am J Physiol Heart Circ Physiol,2002,282(1):281～291.
9Skyschally A,Schulz R,Gres P.Attenuation of ischemic preconditioning in pigs by scavenging of free oxyradicals with ascorbic acid[J].AJP-Heart,2003,284:698～703.
1Maulik N, Watanahe M, Zu YL, et al. Ischemic preconditioning triggers the activation of MAP kinases and MAPKAP kinase 2 in rat hearts[J]. FEBS Lett, 1996,396(2-3) :233-237.
2Fryer RM, Schuhz JE, Hsu AK, et al. Importance of PKC and tyrosine kinase in single or multiple cycles of preconditioning in rat hearts[J].Am Physiol, 1999,276(4 Pt 2) :H1229-1235.
3Saurin AT, Martin JL, Heads RJ, et al. The role of differential activation of p38-mitogen-activated protein kinase in preconditioned ventricular myocytes[J]. FASEB ,2000,14(14) :2237-2246.
4Nakano A, Baines CP, Kim SO, et al. Ischemic preconditioning activates MAPKAPK2 in the isolated rabbit heart : evidence for involvement of p38 MAPK[J] .Circ Res,2000,86(2) : 144-151.
5Mocanu MM, Baxter GF, Yue Y, et al. The p38 MAPK inhibitor, SB203580,abrogates ischaemic preconditioning in rat heart but timing of administration is critical[J]. Basic Res Cardiol,2000,95(6) :472-478.
6Fryer RM, Patel HH, Hsu AK, et al. Stress-activated protein kinase phosphorylation during cardioprotection in the ischemic myocardium[ J ]. Am J Physiol Hear Circ Physiol, 2001,281 (3) : H 1184-1192.
7Kitakaze M, Minamlno T, Node K, et al. Activation of ecto-5′-nucleotidase and cardioprotection by ischemic preconditioning [ J]. Basic Res Carol, 1996,91 ( 1 ) :23-26.
8Gross GJ,Auchampach JA. Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs[J]. Circ Res 1992,70(2) : 223-233.
9Pain T,Yang XM, Critz SD, et al. Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals[J]. Cire Res,2000,87(6) :460-466.
10Banerjee A, Locke-Winter C, Rogers KB, et al. Preconditioning against myocardial dysfunction after ischemia and reperfusion by an alpha 1-adrenergic mechanism[J]. Circ Res, 1993,73(4) :656-670.
7Ruiz GinesJA, Lopez Ongil S, Gonzalez Rubio M, et al. Reactive oxygen species induce proliferation of bovine aortic endothelialcells [J]. J Cardiovasc Pharmacol, 2000, 35 (1): 109- 113.
8Tanaka M. Phamacologic and clinical profile of the free radical scavenger edaravone as a neuro-protective agent [J] Nippon Yakurigaku Zasshi, 2002, 119 (5): 301-308.
9Tsujita K, Shimomura H, Kawano H, et al. Effects of edaravone on reperfusion injury in patients with acute myocardial in farction[J].A mJ Cardiol, 2004, 94 (4): 481-484.
10Sukmawan R, Yada T, Toyota E, et al. Edaravone preserves coronary microvascular endothelial function after ischemia/reperfusion on the beating canine heart in vivo [J]. Pharmacol Sci, 2007, 104 (4), 341- 348.
