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过氧化物酶体增殖物激活受体γ与骨髓干细胞分化及骨质疏松的研究进展

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摘要 过氧化物酶体增殖物激活受体γ属于该受体超家族成员,参与细胞的分化、生长及凋亡。在骨髓微环境中是间充质干细胞向脂肪细胞分化的主要转录调控因子。近年来关于过氧化物酶体增殖物激活受体γ影响骨髓微环境中成骨细胞和破骨细胞分化及凋亡的研究日益深入,在分子水平为阐明骨质疏松症的病理机制提供了新的研究方向。
作者 朱亦堃 乔振华
机构地区 山西医科大学第二临床医院
出处 《国外医学（老年医学分册）》 2005年第4期177-181,共5页 Foreign Medical Sciences(Geriatrics)
关键词 过氧化物酶体增殖物激活受体Γ 干细胞分化 骨髓微环境 转录调控因子 脂肪细胞分化 间充质干细胞 破骨细胞分化 骨质疏松症 家族成员 成骨细胞 病理机制 分子水平 凋亡
分类号 R580 [医药卫生—内分泌]
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参考文献21

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国外医学（老年医学分册）
2005年 第4期

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