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结核分支杆菌重组BCG疫苗研究进展 被引量:6

Advances in the research of recombinant BCG vaccines against Mycobacterium tuberculosis
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摘要 结核分支杆菌引起的结核病是一种人兽共患的慢性传染病,短程督导化疗是治疗该病的主要措施,卡介苗是预防该病的唯一疫苗,但其免疫效果极不稳定。文章介绍了7种结核分支杆菌重组BCG疫苗构建及其免疫机制等方面的研究进展。 Tuberculosis (TB) caused by Mycobacteria tuberculosis (MTB) is one type of zoonotic, chronic, and infectious disease. Directly observed treatment short-course (DOTS) is a major strategy for treating TB. Bacillus Calmette-Guerin (BCG), the only vaccine to prevent TB, has had no constant immune efficacy. This article clarifies advance in the research of construction and immune responses of 7 types of recomhinant BCG vaccines against MTB.
出处 《免疫学杂志》 CAS CSCD 北大核心 2005年第B06期20-24,共5页 Immunological Journal
基金 国家自然科学基金(30200239)重庆市科委自然科学基金(03-43-8)重庆市卫生局自然科学基金(01-2-049 03-2-099)重庆市高等学校优秀中青年骨干教师资助项目
关键词 结核分支杆菌 重组BCG疫苗 Mycobacteria tuberculosis Reconibinant BCG vaccine
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