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非瓣膜病心房颤动转复窦性心律复发影响因素的研究 被引量:29

Predictors in Recurrence of Cardioversion of Atrial Fibrillation With Nonvalvular Disease.
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摘要 为探讨非瓣膜病心房颤动(简称房颤)转复窦性心律后的远期复发率及影响因素。选择2000~2002年住院诊断房颤,并进行药物或电转复后成功者,随访1年比较房颤复发与未复发患者的临床特征。进行Logistic回归分析预测房颤复律后复发的独立危险因素。结果:386例房颤患者复律成功,1年后135例复发,复发率为35%,以复律后1周内发生率最高(53%)。复发与未复发组在年龄、复律方法、基础心脏疾病、复律后是否用抗心律失常药物等方面没有显著差异。预测房颤复发的独立危险因素为左房内径≥50mm(OR=1.86),复律前房颤持续≥7天(OR=2.08)和房颤病程≥3个月(OR=1.77)。结论:左房大小和房颤持续时间是房颤复律后复发的重要预测因素。 The aim of this study is to analysis the relationship of clinical variables to the recurrence of atiral fibrillation after cardioversion to optimize the indication for rhythm control. Retrospective study analysed medical records of the atrial fibrillation patients who have undergone cardioversion from 2000 to 2002. The univariate and multivariate associations of immediate efficacy of cardioversion and long-term results with clinical variables were analyzed. Results: 386 patients who had undergone pharmacological cardioversion or electrical cardioversion were enrolled. Almost half of the patients relapsed within 1 week after successful cardioversion. At the end of one year follow-up, 135 patients (35%) recovered from atrial fibrillation. There were no significant difference between the recurrence group and unrecurrence group in age, heart disease and the methodology of cardioversion. The predictors for the recurrence of atrial fibrillation were diameter of the left atrium ≥50mm(OR=1.86, 95%CI 1.02-3.69, P=0.0472),pre-cardioversion duration ≥7 days (OR=2.08, 95%CI 1.19-3.65, P= 0.01) and the duration of atrial fibrillation (OR=1.77, 95%CI 1.01-3.06, P= 0.0456). Conclusions:The enlargement of left atrium and long duration of atrial fibrillation before cardioversion show less successful rate and more recurrence in the future
出处 《中国心脏起搏与心电生理杂志》 2005年第3期172-174,共3页 Chinese Journal of Cardiac Pacing and Electrophysiology
基金 卫生部科技专项基金资助项目(WKZ2001108)
关键词 心血管病学 心房颤动 复律 复发 窦性心律 Cardiology Atrial fibrillation Cardioversion Recurrence Sinus rhythm
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参考文献10

  • 1The atrial fibrillation follow-up investigation of rhythm management(AFFIRM) investigators. A comparison of rate control and rhythm control in patients with atrial fibrillation [J]. Engl J Med, 2002,347(23):1825.
  • 2Saxonhouse SJ, Curtis AB. Risk and benefits of rate control versus maintenance of sinus rhythm [ J ]. Am J Cardiol, 2003, 91 ( suppl) : 27D.
  • 3Van Gelder IC, Crijns H J, Tieleman RG, et al. chronical atrial fibrillation: Success of serial cardioversion therapy and safety of oral anticoagulation [J]. Arch Intern Med, 1996, 2585.
  • 4Crijns HJGM, Noord TV, Von Gelder IC. Recurrence of atrial fibrillation :Success of serial cerdioversion therapy and safety of oral anticoagulation [ J ]. Arch Intern Med, 1996,2585.
  • 5Pandazi C, Bianconi L, Villani M, et al. Electrophysiology characteristics of the human atria after cardioversion of persistent atrial fibrillation [ J ]. Circulation, 1998, 98 : 2860.
  • 6李悦.心房颤动与心房结构重构[J].中国心脏起搏与心电生理杂志,2003,17(3):227-229. 被引量:15
  • 7Tieleman RG, Van Gelder IC. Crijns HJGM, et al. Early recurrences of atrial fibrillation after electrical cardioversion: A result of fibrillation-induced electrical remolding of the atria [ J ] . J Am Coll Cardiol, 1998, 31 : 167.
  • 8Fumagalli S, Boncinelli L, Bondi E, et al. Dose advanced age affect the immediate and long-term results of direct-current external cardioversion of atrial fibrillation [ J ]. J Am Geriatr Soc, 2002, 50(7): 1192.
  • 9Schannwell CM, Schoebel FC, Marx R, et al. Is cardioversion for atrial fibrillation in the elderly a useful option[ C]. Program and abstracts of the Ⅹ Ⅹ Ⅲ congress of the European Society of Cardiology;September 1-5,2001, Stockholm, Sweden. Abstract 739.
  • 10Madrid AH, Bueno MG, Rebollo J MG, et al. Use of Irbesartan to maintain sinus rhythm in patients with long-lasting persistent atrial fibrillation: A prospective and randomized study [ J ]. Circulation,2002, 106:331.

二级参考文献20

  • 1Boyden PA,Tilley LP,Pham TD,et a1.Effects of left atrial enlargement on atrial transmembrane potentials and structure in dogs with mitral valve fibrosis[J].Am J Cardiol,1982,49:1 896.
  • 2Ausma J,Wijffel M,Thone F,et a1.Structural changes of atrial myocardium due to sustained atrial fibrillation in the goat[J].Circulation,1997.96:3 157.
  • 3Schotten U,Ausma J,Stellbrink C,et a1.Cellular mechanisms of depressed atrial contractility in patients with chronic atrial fibrillation[J].Circulation,2001,103:691.
  • 4Aime-Sempe C,Folliguet T,Ruker-Martin C,et a1.Myocardial cell death in fibrillating and dilated human right atria[J].J Am Coil Cardial,1999,34:1 577.
  • 5Wouters L,Liu GS,Flameng W,et a1.Structural remolding of atrial myocardium in patients with cardiac valve disease and atrial fibrillation[J].Exp Clin Cardiol,2001,5:158.
  • 6Yue LX,Melnyk P,Gaspo R,et a1.Molecular mechanisms underlying ionic remolding in a dog model of atrial fibrillation[J].Circ Res,1999,84:776.
  • 7Van Wagoner DR,Pond AL,McCarthy PM,et a1.Outward K^+ current densities and Kv1.5 expression are reduced in chronic human atrial fibrillation[J].Cir Res,1997,80:772.
  • 8Goette A,Arndt M,Rocken C.et a1.Regulation of angiotensln Ⅱ receptor subtypes during atrial fibrillation in humans[J].Circulation,2000,101(236):2 678.
  • 9Nakashima H,Kumagai K,Urata H,et a1.Angiotensin Ⅱ antagonist prevents electrical remolding in atrial fibrillation[J].Circulation,2000,101(22):261.
  • 10Van der Velden HM,Van Kempen MJ,Wijffels MC,et a1.Altered pattern of connexin40 distribution in persistent atrial fibrillation in the goat[J].J Cardiovasc Electrophysiol,1998,9:596.

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