摘要
目的:调查北京地区人群血脂水平和血脂谱现状,为血脂水平划分和血脂异常防治提供客观依据。方法:生活水平较好的男性1752例,女性761例为调查对象,从20～90岁,每10岁1个年龄组各分为7组。按血脂测定标准化方法测定总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白-胆固醇(HDL-C)和低密度脂蛋白-胆固醇(LDL-C)4项血脂水平。结果:TC水平最高男性为5.30mmol/L、女性为5.99mmol/L,高水平年龄在71～80岁;TG水平最高男性为1.87mmol/L,女性为1.77mmol/L,年龄在41～70岁;HDL-C最低水平为1.25mmol/L,各年龄段均在合适水平;LDL-C最高男性为3.46mmol/L,女性为3.78mmol/L,年龄在71～80岁。健康人异常脂蛋白血症发生率(按我国“血脂异常防治建议”血脂水平划分方案划分)为TC36.7%,TG31.22%,HDL-C2.84%,LDL-C12.68%。结论:健康人TC、HDL-C、LDL-C整体水平与90年代相似;TG水平比90年代明显增高。血脂谱以异常高TC占首位,依次为TG、LDL-C、HDL-C。高TG血症发生率(31.22%)与高TC血症发生率(36.7%)相差不多,应重视高TG血症防治。建议人群血脂水平为TC:合适水平<5.72mmol/L;边缘升高5.72～6.24mmol/L;危险水平>6.24mmol/L。TG:合适水平<2.00mmol/L;边缘升高2.00～3.39mmol/L;危险水平>3.39mmol/L。HDL-C:>1.04mmol/L为安全水平;<0.
Objective:To explore the lipids levels and profiles in the healthy volunteers at Beijing, and provide the objective data for underlining lipids levels and preventing dyslipidemia.Methods:1 752 males and 761 females served as subjects, and were divided into seven groups (10 years per group) respectively. Total cholesterol (TC), Triglyceride (TG), high density lipoprotein-cholesterol (HDL-C) and low density lipoprotein-cholesterol (LDL-C) were measured according to the National Standardized Methods.Results:The highest TC level was 5.30 mmol/L and 5.99 mmol/L in the male and female aging from 71~80.The highest TG level was 1.87 mmol/L and 1.77mmol/L in the male and female aging from 41~70.Almost all subjects′ level of HDL-C was at higher level in the different and age groups.The highest LDL-C level was 3.46 mmol/L and 3.78 mmol/L in the male and female aging from 71~80. According to the 'Recommended guidelines for treatment of dyslipidemia of China (1997)', The incidence of dyslipidemia at healthy population was TC 36.7%, TG 31.22%, HDL-C 2.84%, LDL-C 12.68% respectively.Conclusion:The general TC, HDL-C, LDL-C level in healthy subjects was not increased compared with that of the 1990s, but the TG level was increased rapidly. The incidence of dyslipidemia was firstly TC, and TG, LDL-C, HDL-C, secondly. There was no distinct difference between the incidence of high TC and high TG. The results indicate that more attention should be paid to the prevention of the high TG dyslipidemia. Lipids levels should be: TC: desires level <5.72 mmol/L; verge level 5.72~6.24 mmol/L; risk level >6.24 mmol/L.TG: desires level <2.00 mmol/L; verge level 2.00~3.39 mmol/L; risk level >3.39 mmol/L; HDL-C desires level >1.04 mmol/L; risk level <0.99 mmol/L; LDL-C: desires level <3.64 mmol/L; verge level 3.64~4.16 mmol/L; risk level >4.16 mmol/L.
出处
《中国卫生检验杂志》
CAS
2005年第6期659-662,共4页
Chinese Journal of Health Laboratory Technology
