摘要
采用同种内耳抗原免疫豚鼠，６周后免疫组动物５０耳有３３耳（６６％）出现单侧或双侧感音神经性聋。内耳火棉胶切片，酶组织化学，免疫组织化学和透射电镜以及体液免疫反应等观察，确认为免疫反应引起的感音神经性聋。
The Guinea Pigs Were Immunized With The
Homogeneous Antigen. Six Weeks After Im-Munization, Sensorineural Hearing Loss Occured In
33 Ears Among 25 Immunized Animals,The Inci-Dence Of Hearing Loss Was 66 Per
Cent(33/50). The Pathological Changes Of Inner Ear Of ImmunizedAnimal Were Observed By
Ce11uloid Section, Enzyme Histochemistry, Transmission ElectromicroscopeAnd
Immunohistochemistry, And The Results Confirmed That The Scnsorineural Hearing Loss Was
Indn-Ced By The Immune Reaction. The Pathological Characteristics And The Pathogenesis Of
AutoimmuueSensorineural Hearing Loss Were Discussed.
出处
《军医进修学院学报》
CAS
1994年第4期251-254,共4页
Academic Journal of Pla Postgraduate Medical School
关键词
自身免疫病
听力障碍
疾病模型
Autoimmune Diseases
Hearing Disorders
Disease Models, Animal
Immunohistochemis-Try
