期刊文献+

异丙酚-氯胺酮复合静脉麻醉在小儿中小手术中的应用 被引量:14

Application of propofol-ketamine combined intravenous anesthesia in children's mini-middle-operations
暂未订购
导出
摘要 目的观察异丙酚-氯胺酮复合静脉麻醉与单纯氯胺酮麻醉在小儿中小手术中对呼吸循环功能及术后恢复情况的影响.方法30例中小手术患儿分成两组:异丙酚-氯胺酮(PK)组15例,术中异丙酚4~6 mg/(kg·h)与氯胺酮2~3 mg/(kg·h)混合液持续静脉泵入;氯胺酮(K)组15例,术中氯胺酮1~2mg/(kg·h)间断静脉注射.结果术中PK组循环功能较K组稳定,术中发生肢体不自主运动及眼球震颤较K组少;PK组术中氯胺酮用量、术后恢复时间与K组比较,差异有显著性意义(P<0.05).结论异丙酚-氯胺酮复合静脉麻醉能使小儿中小手术麻醉更平稳、术后苏醒更快,更适合于小儿中小手术的麻醉. Objective To observe the influence of propofol-ketamine combined intravenous anesthesia and ketamine intravenous anesthesia on breath and circulation functions and the postoperative recovery for children undergoing mini-middle-operations. Methods Thirty children undergoing mini-middle-operation were randomly divided into two groups: the propofol-ketamine group (15 cases), continuous infusion of propofol [4~6 mg/(kg·h) ] and ketamine [2~3 mg/(kg·h)]during the operation; the ketamine group (15 cases), intermittent intravenous injection of ketamine [1~2 mg/kg] during the operation. Results During the operation the function of circulation in the propofol-ketamine group was more steady than that in the ketamine group. The incidences of involuntary movement and nystagmus were less in the propofol-ketamine group than the ketamine group. The amount of ketamine was less and the time for recovery was shorter in the propofol-ketamine group than the ketamine group (P<0.05). Conclusion Compared with intravenous ketamine anesthesia, propofol-ketamine combined anesthesia is more steady and faster to awake after operation and therefore more suitable to children's operation.
出处 《实用医院临床杂志》 2005年第3期38-39,共2页 Practical Journal of Clinical Medicine
  • 相关文献

参考文献6

二级参考文献9

  • 1Vinik HR, Bradley EL, Kissin I. Isobolographic analysis of propofolthiopental hypnotic interaction in surgical patients. Anesth Analg, 1999,88 : 667 -670.
  • 2Hui TW, Short TG, Hong W, et al. Additive interactions between propofol and ketamine when used for anesthesia induction in female patients. Anesthesiology, 1995,82 : 641-647.
  • 3Ronald J. Statistical analysis of drug combinations for synergism. Pain,1992 , 49 : 93-97.
  • 4Ronald J, Tallarida T, Porreca F, et al. Statistical analysis of drug-drugand site-site interactions with isobolograms. Life Sci, 1989,45: 947-961.
  • 5Kissin I, Vinik HR, Castillo R, et al. Alfentanil potentiates midazolam-induced unconsciousness in subanalgesic doses. Anesth Analg, 1990,71:65 -69.
  • 6Berenbaum MC. What is synergy? Pharmacol Rev, 1989,41:93-141.
  • 7Harriet MB,Bret R,Fulton,et al.Propofol:an update of its use in anaesthesia and conscious sedation[].Drugs.1995
  • 8Paul FW.Textbook of Intravenous Anesthesia[]..1997
  • 9许幸,魏秀兰,吴新民.序贯试验法测定异丙酚诱导时的BIS_(50)和ED_(50)[J].中华麻醉学杂志,2001,21(1):7-9. 被引量:31

共引文献234

同被引文献60

引证文献14

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部