摘要
目的探讨网织血小板、血小板生成素对诊断特发性血小板减少性紫癜的意义。方法流式细胞仪检测网织血小板所占比值,酶联免疫吸附试验检测血小板生成素,血细胞自动检测仪检测血小板和平均血小板容积,骨髓涂片计数巨核细胞。结果血小板减少性紫癜患者组网织血小板所占比值高于其他各组,血小板生成素接近对照组,巨核细胞增多伴平均血小板容积增大和网织血小板所占比值升高。结论联合检测网织血小板和血小板生成素有助于区别不同原因所致血小板减少性疾病,对诊断血小板减少性紫癜有一定的临床价值。
Objective To study the significance of reticulated platelet and thrombopoietin in the diagnosis of idiopathic thrombocytopenic purpura. Methods Reticulated platelet percent was analyzed via flow cytometry, plasma thrombopoietin was examined by ELISA, platelet and mean platelet volume were measured by automized machine,and megakaryocyte was counted through bone marrow staining. Results Reticulated platelet percent of idiopathic thrombocytopenic purpura patients' group were higher than other groups,thrombopoietin of this group was about the same to control group, and increased megakaryocytosis of this group was associated with larger mean platelet volume and higher reticulated platelet percent. Conclusion Examination of reticulated platelet percent and thrombopoietin is helpful to classify the patients with thrombocytopenia into different categories and may be of a value in the diagnosis of idiopathic thrombocytopenic purpura.
出处
《山西医科大学学报》
CAS
2005年第3期330-333,共4页
Journal of Shanxi Medical University
