摘要
目的观察电化学对晚期食管癌合并严重梗阻的治疗效果.方法应用我国研制的导管电极治疗70例晚期食管癌合并梗阻,其中65例为原发性晚期食管癌梗阻,5例为术后吻合口狭窄.全部病例均为Ⅲ、Ⅳ度梗阻,且不能接受手术或放、化疗.通过导管电极采用直流电治疗1～4次.结果完全缓解(CR)19例;部分缓解(PR)35例;稍有改善(NC)9例;病情无改善(PD)7例.总有效率(CR+PR)为77.1%(54/70).结论本方法简便易行,安全有效,创伤小、恢复快,可明显改善患者的进食梗阻,提高患者生存质量,为治疗晚期食管梗阻提供了一种新的有效方法.
Objective To observe the effect of electrochemotherapy on advanced esophageal carcinoma complicated with obstruction. Methods Seventy patients with advanced esophageal carcinoma complicated with obstruction, including 65 with primary obstruction of advanced esophageal carcinoma and 5 with anastomotic stenosis after surgery were treated by electrochemotherapy using a catheter electrode. All the patients showed obstruction by degrees Ⅲand Ⅳ and could not accept the surgery, radiotherapy or chemotherapy. They were treated 1 to 4 times by direct current through a catheter electrode. Results DegreeⅠ(CR) was in 19 patients, degreeⅡ(PR) in 35, degree Ⅲ(NC) in 9 and degree Ⅳ (PD) in 7. The total effective rate (CR+PR) was 77.1%. Conclusion This method is easy to operate, safe and effective. The trauma caused by this method is slight and can be recovered soon. It can improve the symptom of obstruction due to taking food, and the patients' survival level is enhanced evidently. This is a new effective approach for advanced esophageal carcinoma with obstruction.
出处
《山西医科大学学报》
CAS
2005年第3期329-330,共2页
Journal of Shanxi Medical University
关键词
食管肿瘤
电疑术
药物疗法
esophageal neoplasma
electrocoagulation
drug therapy
