摘要
目的:探讨不同剂量丙种球蛋白(IVIG)联合地塞米松治疗小儿急性特发性血小板减少性紫癜(ITP)的临床疗效。方法:将43例急性ITP住院患儿分为3组,给予IVIGI组0.4～0.5/kg·d×3天、Ⅱ组0.4/kg·d×5天、Ⅲ组1.0/kg·d×2天。联合使用地塞米松1mg/kg·d静滴,5天后减量或改为口服强的松逐渐减量,总疗程3￣4周。结果:三组治疗后的显效率和有效率分别为:I组86.67%、93.33%,Ⅱ组83.33%、94.44%,Ⅲ组90%、90%。三组治疗后的血小板达正常值时间分别为:I组3.62±1.66天,Ⅱ组4.27±1.44天,Ⅲ组3.89±2.09天。结论:三种剂量IVIG联合地塞米松治疗小儿急性ITP的临床疗效无显著性差异。
Objective To explore ITP treated with different dose gammaglobulin and Dexamethasone. Methods 43 cases were divided into three groups, group Ⅰ—the dosage of gammaglobulin 0.4～0.5/kg·d×3 days,group Ⅱ—0.4/kg·d×5 days, group Ⅲ—1.0/kg·d×2 days. Three groups were treated with Dexamethasone intravenous droping 1mg/kg·d×5 days .After 5 days Dexamethasone was decreased or Prednison was given and decreased slowly, which lasted 3~4 weeks. Results Three groups' frank of distinc availability and availability were respectively 86.67% and 93.33% in group I, 83.33% and 93.44% in group Ⅱ, 90% and 90% in group Ⅲ. The platelet of three groups reached normal in 3.62±1.66 days(Ⅰ), 4.27±1.44 days(Ⅱ), 3.89±2.09 days(Ⅲ). Conclusion There were no significant differences of using different doses.
出处
《安徽卫生职业技术学院学报》
2005年第3期33-34,共2页
Journal of Anhui Health Vocational & Technical College
