摘要
目的探讨难治性血小板减少性紫癜的有效治疗方法。方法把资料完整的43例患儿分为三组,A组为长春新碱组,B组为干扰素组,C组为丙种球蛋白组。回顾性对比研究三种疗法的疗效。结果A、B、C三组的总有效率分别为38.5%、90.9%、91.7%。经χ2检验,A组与B组之间(χ2=6.99,P<0.05),A组与C组之间(χ2=7.67,P<0.05)均有显著性差异;B组与C组之间(P>0.05)无显著性差异。结论干扰素、丙种球蛋白疗效好、不良反应少,患儿易耐受,是难治性血小板减少性紫癜较理想的治疗方案。长春新碱疗效次之,且不良反应大,只在一些难治性病例应用。
Objective To study the effective therapy of idiopathic thrombocytopenic purpura. Methods The 43 children with idiopathic thrombocytopenic purpura with full data were divided into three groups, A:vincristine group, B: interferone group, C: R-globulin group, effects of the three therapies were analysed retrospectively. Results [JP3]The total efficiencies were A: 38.5%, B: 90.9 %and C 91.7% respectively. After verified by χ2 test,there was significant difference between group A and B(χ2=6.99, P<0.05) and between group A and C (χ2=7.67, P<0.05).There was no significant difference between group B and C (P> 0.05 ). Conclusion Interferone and R-globulin are effective way , with little side-effect, more acceptable .They are ideal therapies for idiopathic thrombocytopenic purpura . Vincristine take the second place, also have great side-effect, only used on some cases that hard to cure.[JP]
出处
《医药论坛杂志》
2005年第10期30-31,共2页
Journal of Medical Forum
