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中国与美国膳食脂肪酸与胆固醇对血清胆固醇作用强度的比较 被引量:12

A comparative meta-analysis on the effects of dietary fatty acids and cholesterol on serum total cholesterol between Chinese and American population samples
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摘要 本研究以北京及广州男性工人及农民样本人群的膳食与血清胆固醇关系的资料与美国西方电气公司职工的一组相似资料进行对比,以比较在中国低脂肪低胆固醇膳食条件下与美国高脂肪高胆固醇膳食条件下膳食脂质对血清胆固醇的作用强度。结果表明:在此组中国研究人群中膳食饱和脂肪酸和胆固醇及其综合分值对血清胆固醇的作用强度不低于美国研究人群。提示在膳食迅速变化的时期,应注意控制饱和脂肪和胆固醇摄入量的增长。 Abstract For answering the question of whether dietary lipids have the similar strength of effects on serum cholesterol in a Chinese population with low dietary fat as in the Western populations,a comparative meta-analysis was done by using the baseline data of dietary survey,serum cholesterol measurements in subsamples of Beijing and Guangzhou urban and rural populations of the PRC-US Collaborative Study on cardiovascular and cardiopulmonary diseases, compared with the similar data of Western Electric Study of the United States published in 1981 on the New England Journal of Medicine. The participants of both studies included middle aged men employed by the industrial company or farmers living in the suburb of big cities. 24-hour dietary recall (3 days in autumn and spring respectively) method was used in Chinese samples, food frequency questionaire was used in Western Electric Study (WE). Results showed. 1. The mean daily intake of SFA% kcal and dietary cholesterol (mg/ 1000 kcal) were less than half of those of the WE group, PuFA% kcal was 1.5 times that of the WE group. Dietary Keys score was 26.9 and 60.2 for Chinese and WE group respectively. 2. Mean serum cholesterol levels of the Chinese and WE study group was 173 and 247 mg/dl respectively, mean BMI was 21.6 and 25.4 respectively. 3. Multiple regression analyses within Chinese and WE group showed very similar direction, significance of associations of dietary Keys score, SFA% kcal, PuFA% kcal,and cholesterol to serum cholesterol. It is very interesting to find that the strength of effects estimated by regression coefficients was very similar between the two groups. Conclusion:The effects of dietary lipids factors on serum cholesterol is a continuous one,even in a population with low dietary fat and low serum cholesterol like Chinese.Once the dietary SFA and cholesterol increase as the lifestyle westernized, the serum cholesterol will rise rapidly. This result calls for the urgent need to educate the Chinese populations to keep on healthy diet.
出处 《中华心血管病杂志》 CAS CSCD 北大核心 1994年第1期20-23,共4页 Chinese Journal of Cardiology
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  • 1周北凡,中国循环,1992年,7卷,49页

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