摘要
研究了大白鼠去神经带血管骨骼肌移植后的神经再生过程,同时对切除肌膜和保留肌膜神经再生的结果进行了比较。经过术后不同时期进行的肌电图、组织学、组织化学及电子显微镜等项检查,结果显示:①去神经带血管移植肌可以通过一个正常神经支配的肌肉获得神经支配。②这一过程是通过肌肉神经再支配的方式进行。③去神经带血管肌肉移植后4周即出现初期神经再支配的证据,14周后神经再支配已比较完全。④移植肌的筋膜妨碍神经再生过程,移植前必须予以切除。
This study was designed to search for some further information about the reinnervtion of the denervated but vascular preserved skeletal muscle by muscular neurotization.In our experiment,rats were assigned randomly to either of two groups:the group with the muscle fascia intact and the group with the muscle fascia removed.The fibularis nerve being removed,the fibularis longns muscle was transplanted to the gastrocnemiu muscle.At different times after operation, the grafted muscle was studied under electrornyogram, electronic microscope and histological and histochemical examination.The results showed that the grafted muscle was reinnervated completely by tibialis nerve in the group with muscle fascia removed,however only few reinnervation occurred in the group with muscle fascia intact.It is concluded that muscle fascia is an obstacle to reinnervation.In order to achieve a successful reinnervation,the muscle fascia must be removed.The findings agree with the clinical results.
出处
《中华小儿外科杂志》
CSCD
1994年第4期237-239,共3页
Chinese Journal of Pediatric Surgery
关键词
移植术
去神经
骨骼肌
肛门失禁
Nerve regeneration
Denervation
Skeletal muscle
vascularized
