摘要
摘要采用特异的胃动素（ＭＴＬ）抗体，通过放射免疫法对３４２例成人１３种体液内ＭＴＬ进行了较为系统的观察。结果表明：１３种液体内ＭＴＬ均值以十二指肠液含量最高（３６５．４±８２．６ｐｍｏｌ／Ｌ），较血浆（１４１．２±５１．４ｐｏｍｏｌ／ｌ）高２．６倍，较血清（８０．１±３４．０ｐｍｏｌ／ｌ）高４．７倍，而胆汁ＭＴＬ水平最低（＜１０ｐｍｏｌ／Ｌ）。各体液ＭＴＬ梯度依次为：十二指肠液、血浆、胃液、唾液、胸水、腹水、血清、尿液、脑脊液、羊水、乳汁、精液、胆汁。胃十二指肠液，ＭＴＬ分别与血浆ＭＴＬ呈正相关（Ｐ＜０．０１）。研究结果首次揭示了人体１３种体液中ＭＴＬ分布及关系，并推测ＭＴＬ分泌细胞具有腔内分泌作用。
his paper discussed motilin(MTL)levels of l3 kinds of body fiuids as determined by
RIA in342 normal adults.The results showed that the average MTL level of the duodenal
juice(365.4±826pmol/L) was the highest among body fluids,2. 6 times higher than that of the
plasma (141.2±51.4pmol/L)and 4.7 tilnes higher than that of serum (80.1±34.0 pmol/L).The
MTL Ievel of bile(<10pmol/L) was the lowest.The MTL levels of body fluids were in the following
order:duodenaljuice,plasma, gastric juice, saliva, pleural ascitic fluid were higher than that of
the serum. Therewas a positive correlation between MTL level of the gastric or duodenal juice
and that of plasma(P<0.05).This study first shows the distribution and relationship of MTL in
various body fluids,and also comfirms MTL may be secrefed into the gastro-intestinal lumen by
M0 cell.
出处
《中华消化杂志》
CAS
CSCD
北大核心
1994年第2期96-98,共3页
Chinese Journal of Digestion
