摘要
目的:探讨引用“川崎病疑似病例”这一概念,对实现川崎病早期用阿司匹林(ASP)及大剂量静注丙种球蛋白(IVIG)治疗的实用性和可行性。方法:对入选的36例川崎病疑似病例早期应用ASP和IVIG治疗,并对临床资料进行分析总结。结果:36例中最后有32例确诊为川崎病,初诊时确诊5例,约占13.9%,其余为疑似病例,在平均病程6.93d开始上述治疗,比平均确诊日期(10.32d)明显提前,冠状动脉损害发生率为6.25%,明显低于传统治疗。最后诊断非川崎病的4例未因上述治疗加重或延误病情。结论:引用川崎病疑似病例这一概念,能有效实现早期应用ASP、IVIG治疗川崎病,降低冠状动脉损害发生率,安全实用可行。
Objective:To quote a concept of “Suspected Case of Kawasaki Disease” in order to define the practicability and feasibility of early treatment of it with ASP and IVIG in high dosage by IV push.Methods: 36 suspected cases of Kawasaki disease(KD) were treated with ASP and IVIG at the early stage,and then the clinical data were analysed and summarized.Results:From 36 suspected cases,32 cases were confirmed to suffer from KD. When first diagnosed 5 cases(13.9%) were proven to have this disease,and the remainders were suspected.After 6.93 days(at average)of the disease onset the aforementioned treatment began to be undertaken.The time of first visit to a doctor was earlier than the average visit time(10.32 days),and the incidence of coronary lesion(6.25%)was lower than that taken out by traditional treatment.In the four cases of non-KD which was diagnod at last the disease was not worsening because of above treatment.Conclusion:Quoting the concept of Suspected Cases of KD can successfully help the doctor to early cure the disease with ASP and IVIG,thus decreasing the incidence of coronary lesion.
出处
《医学理论与实践》
2005年第6期655-657,共3页
The Journal of Medical Theory and Practice
