摘要
目的:探讨川崎病(KD)早期诊断要点与减少心血管损伤的治疗方法。方法:对86例确诊KD的住院患儿的临床特点、实验室检查、心电图及超声心动图进行检查,对定期随访结果进行分析。结果:临床特点中肛周红与卡瘢红发生率分别为53.4%、40.7%;超声心动图检查发现冠状动脉扩张28例,冠状动脉瘤5例;用静脉丙种球蛋白(IVIG)治疗的冠状动脉病变发生率33.3%,仅用阿司匹林治疗的冠状动脉病变发生率64.2%,7d内使用IVIG治疗的冠状动脉病变发生率9.6%(P<0.01)。结论:对非典型KD应及时做超声心动图检查,早期足量使用IVIG可减少KD并发冠状动脉病变的发生。
Objective: To explore the methods of early diagnosis and the therapeutic measure of reducing cardiovascular damage of Kawasaki Disease(KD). Methods: The clinical symptoms, lab-examinations, electro cardiograph(ECH) and echocardiogram( ECM) examinations of 86 in patient cases of KD were analyzed and result from regular follow-up were conducted. Results: incidence of perianal redness and redness of BCG vaccination scar is 53. 4% and 40. 7% respectively; coronary artery dilatation was found in 28 cases, while coronary artery tumor-like dilatation in 5 cases by in ECM examination; the incidence of coronary artery injury was 33. 3% in cases receiving IVIG therapy, while 64. 2% in cases only receiving aspirin therapy; incidence of coronary artery injury was 9. 6% in cases receiving IVIG therapy within 7 days (F<0. 01). Conclusion: To make early diagnosis of typical KD cases,echocardiogram examination should be done earlier Full - dose IVIG therapy in early stage can reduce the incidence of coronary artery injure.
出处
《河北北方学院学报（医学版）》
2005年第2期39-41,共3页
Journal of Hebei North University:Medical Edition
关键词
川崎病
冠状动脉病变
早期诊断
防治
kawasaki disease
impairmeent of cardi voscularststem artery
early diagnosis
prevention and cure
