摘要
目的:观察罗红霉素在支气管哮喘治疗中的抗炎活性。方法:将2 0 0 4年月4月～2 0 0 5年1月1 1 6例门诊气管支哮喘患者分为治疗组甲,乙及对照组,甲、乙两治疗组分别予甲强龙及罗红霉素辅助治疗,对比其治疗前后临床症状,体征及免疫等各方面表现。结果:两治疗组与对照组的近期疗效比较均显著性差异(P <0 .0 1 ) ,两治疗组有效率比较无显著性,在EOS方面,两治疗组治疗后与治疗前比较均有显著性差异(P <0 . 0 1 ) ,而两治疗后比较无显著性差异(P >0 . 0 5) ;对照组治疗前后比较无显著性差异(P >0 . 0 5)。结论:在支气管哮喘的治疗中,罗红霉素的抗炎作用与皮质激素效果相仿。
Objective:To observe the anti-inflammation activity of Roxithromycin in treatment of bronchial asthma.Methods:116 cases of bronchial asthma were divided into three groups randomly:treated group A,treated group B and the control group. Medrol was given group A and roxithromyain was given group B as supportive therapy. The symptoms,physical signs,immunity and so on before and after the treatment in the three group were compared.Results: The curative efficary in the two treated groups was obviously higher than that in the control group( P <0.01),and the difference between the two treated groups was not obvious.In the two treated groups,the EOS level after treatment obviously declined copmpared with that before treatment ( P <0.01).The difference of EOS in the two treated groups after therapy was not obvious( P >0.05),while in the control group it was obvious ( P >0.05) before and after therapy. Conclusion:In the treatment of bronchial asthma Roxthromycin and cortin have a similar anti-inflammation activity.
出处
《医学理论与实践》
2005年第5期522-523,共2页
The Journal of Medical Theory and Practice
