1Parnham MJ.Immunomodulatory effects of antimicrobials in the therapy of respiratory tract infections.Curr Opin Infect Dis,2005,18:125-131.
2Molinari G,Guzman CA,Pesce A,et al.Inhibition of Pseudomonas aeruginosa virulence factors by subinhibitory concentrations of azithromycin and other macrolide antibiotics.J Antimicrob Chemother,1993,31:681-688.
6Park SJ,Lee YC,Rhee YK,et al.The effect of long-term treatment with erythromycin on Th1 and Th2 cytokines in diffuse Panbronchiolitis.Biochem Biophys Res Commun,2004,324:114-117.
7Jaffe A,Bush A.Cystic fibrosis:review of the decade.Monaldi Arch Chest Dis,2001,56:240-247.
8Barker PM,Gillie DJ,Schechter MS,et al.Effect of macrolides on in vivo ion transport across cystic fibrosis nasal epithelium.Am J Respir Crit Care Med,2005,171:868-871.
9Garey KW,Alwani A,Danziger LH,et al.Tissue reparative effects of macrolide antibiotics in chronic inflammatory sinopulmonary diseases.Chest,2003,123:261-265.
10Kawamura-Sato K,Iinuma Y,Hasegawa T,et al.Effect of subinhibitory concentrations of macrolides on expression of flagellin in Pseudomonas aeruginosa and Proteus mirabilis.Antimicrob Agents Chemother,2000,44:2869-2872.
5[1]Tateda K, Hirakata Y, Furuya N, et al. Effects of subMIC of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa [J]. Antimicrob Agent Chemother, 1987; 31:1502
6[2]Soboh F, Khoury A E, Iamboni A C, et al. Effects of ciporfloxacin and protamine sulfate combination against cather-associated Pseudomonas aeruginosa biofilms [J].Antimicrob Agent Chemother, 1995; 39:1281
7[3]Lawrence J R, Korber D R, Hoyle B D, et al. Optical sectioning of microbial biofilms [J]. J Bacteriol, 1991; 173:6558
8[4]Costerton J W. Bacterial biofilms in nature and diseases [J]. Ann Rev Microbiol,1987;41:435
9[5]Tateda K, Ishil Y, Matsymoto T, et al. Direct evidence for anti-pseudomonas activity of macrolides: exposure dependent bactericidal activity and inhibition of protein synthesis by erythromycin clarithromycin and azithromycin [J]. Antimicrob Agent Chemother, 1996; 40: 2271
10[6]Ichimiya T, Takeok K, Hiramatsu K, et al. The influence of azithromycin on the biofilm formation of Pseudomonas aeruginosa in vitro [J]. Chemotherapy, 1996; 42:186
