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超声结合尸检对前列腺外腺良性增生性低回声结节的研究 被引量:7

Study of hypoechoic nodule diagnosis of BPH in outer gland of the prostate by TRUS and autopsy
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摘要 目的 应用经直肠超声(TRUS)结合尸检探讨前列腺外腺是否存在良性增生性结节的可能性。 方法 59例TRUS显示的前列腺外腺低回声结节行定点穿刺活检,HE染色;选取前列腺尸检标本16例,行水槽实验和HE染色。 结果 59例前列腺外腺低回声结节穿刺标本病理诊断为良性前列腺增生(BPH)22例,前列腺癌(PCa)29例,前列腺上皮内瘤变(PIN)1例,前列腺结核(TB)7例。水槽实验提示尸检标本声像图内外腺分界清楚,实质内见多发强回声钙化灶及多发囊肿; 16例前列腺尸检标本HE染色外腺均可见腺体、平滑肌和纤维结缔组织不同程度的增生,病理证实为BPH。 结论 TRUS显示的前列腺外腺低回声结节除了PCa、PIN、TB等疾病之外,还存在良性增生性结节。 ObjectiveTo investigate the possibility of benign prostatic hyperplasia (BPH) in prostatic outer gland by transrectal ultrasound (TRUS) and autopsy examination.MethodsFifty-nine patients were biopsied by TRUS guided in sagittal and longitudinal sections,respectively,because hypoechoic nodules were found in the outer glands of the prostates. The specimens were stained by HE methods.The whole prostate specimens obtained from 16 men at autopsy were studied. Sonogram of the specimens was investigated by putting them in water.Then the specimens were sliced down perpendicularly to the urethra,histologically processed and stained by HE methods.ResultsPathologically,22 of the 59 specimens were of benign prostate hyperplasia (BPH),29 of prostate cancer (PCa),1 of prostatic intraepithelial neoplasia (PIN) and 7 of tuberculosis (TB).A clear-cut interface between inner gland and outer gland, and multiple calculi and cysts were found on sonogram.Pathological diagnosis of BPH of the outer glands was made in all HE-stained autopsied specimens with varying degrees of hyperplasia of the glands, small muscles and stroma.ConclusionsIt is suggested that hypoechoic nodules in outer gland of the prostate by TRUS on sonogram may be benign hyperplastic nodules besides PCa,PIN,and TB.
出处 《中华泌尿外科杂志》 CAS CSCD 北大核心 2005年第5期312-314,共3页 Chinese Journal of Urology
关键词 超声 尸检 前列腺外腺良性增生性低回声结节 诊断 良性前列腺增生 Outer gland of prostate Benign prostate hyperplasia Hypoechoic nodules Biopsy Autopsy
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