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新生儿细菌感染与胰岛素样生长因子Ⅰ(IGF-Ⅰ)关系探讨 被引量:1

A Study on the Relationship between the Insulin Like Growth Factor-Ⅰ(IGF-Ⅰ) and Newborn Bacteria Infection
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摘要 目的:探讨胰岛素样生长因子Ⅰ(IGF- Ⅰ)在新生儿细菌感染时的意义。方法:生后3 d内入院的儿科新生儿病人,入院后予测C 反应蛋白(CRP)、免疫球蛋白M(IgM)、血常规、胸片、血培养以及IGF -Ⅰ。按新生儿感染诊断标准诊断感染组30例,对照非感染组20例。结果:感染组与非感染组比较WBC、CRP、IgM、IGF -Ⅰ有显著差异(P<0.05)。结论: IGF 1 的降低可反映细菌性感染的存在。 Objective: To explore the significance of IGF-Ⅰexpression in the newborns who were infected the bacteria during the newborn period.Methods: Fifty 3-days-old newborns were included in this study.Among them, 30 cases with bacteria infection,20 cases with no infection as normal controls. The samples were assayed for the level of C-reaction protein (CRP),IgM,the blood routine,the blood culture and the IGF-I levels. Results: The levels of WBC,CRP,IgM,IGF-I in infected patients were significantly different from those in normal controls (P< 0.05). Conclusion:The lower expression of IGF-I may help to predict the presence of newborn′s infection.
出处 《中国临床医学》 北大核心 2005年第2期298-299,共2页 Chinese Journal of Clinical Medicine
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