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PYY与肥胖 被引量:1

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摘要 肽YY(PYY)是由回肠细胞在进食时分泌的短肽。研究发现,PYY能够通过调节下丘脑中影响食欲的神经通路来减少食物摄入。它与载脂蛋白AⅣ、Ghrelin等许多影响食欲的因素相互作用,从而在肥胖的发生机制中起重要作用。肥胖个体内源性PYY水平降低,表明PYY缺乏可能与肥胖发生有关。但肥胖个体对PYY抑制食欲的作用不存在抵抗,故外源性补充PYY可能对肥胖的治疗有效。
作者 张贝 李成江
出处 《国外医学(内分泌学分册)》 2005年第B04期6-8,共3页 Foreign Medical Sciences(Section of Endocrinology)
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参考文献15

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同被引文献14

  • 1陈珏,张明岛,肖泽萍.神经性厌食症的社会心理因素[J].上海精神医学,2004,16(5):298-300. 被引量:16
  • 2牟志伟,林冰.对神经性厌食的认识与研究[J].卫生职业教育,2005,23(2):110-111. 被引量:7
  • 3陆洁莉,赵咏桔.瘦素与神经性厌食[J].国外医学(内科学分册),2005,32(11):490-492. 被引量:5
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  • 5杜永平,张月萍,张国成,牛瑜,徐彦博.幼龄厌食大鼠食欲中枢神经元兴奋性的改变[J].神经解剖学杂志,2007,23(1):40-44. 被引量:3
  • 6Hebebrand, Muller, Holtkamp,et al. The role of leptin in anorexia nervosa:elinieal implieations[J].Moleeular Psychiatry, 2007, 12(1):23-359.
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