摘要
实验用微电极细胞外记录方法和脑内立体定住刺激技术，以内脏大神经诱发猫丘脑后核（PO）的单位放电为内脏痛指标，观察电刺激CL对内脏痛放电的影响。电刺激CL可使PO放电受到抑制。侧脑室注射GABA受体阻断剂印防已毒素翻转了CL的即时抑制作用。
The effects of the nucleus central lateralis (CL ) on the unit discharges evoked by the splanchnic afferents in the posterior group of thalamic nuclei (PO) were studied with extracellular microelectrode techniques. In 35 cate. 96 units (98％)producing evoked discharges in PO with the latency range of 30 -150ms were observed. The evoked discharges of 69 units in PO were depressed by stimulating CL with a short train of electric pulse through a hipolar electrode, but the other 27 units were uninfluenced. The inhibition of CL can be classified into 3 forms: the instant inhibition,the delayed inhibition and the continued inhibition. The injection of picrotoxin (1‰, 40μl) into lateral ventricles of the brain could invertthe inhibitory effects of PO cells caused by stimulating CL. The results suggest that there may be direct neryous pathway from CL to PO and some of these neurons may function with GABA with GABA as neurotran mitter .The GABA The CL may execute the instant inhihition through the nervous pathway.It is conefuded that CLhas mbibitory effect on visceral pain and GABA is involved in the inhibitory process.
出处
《针刺研究》
CAS
CSCD
1994年第2期35-38,共4页
Acupuncture Research
