摘要
应用单克隆抗体酶联免疫吸附抑制实验，对我国３个民族８个群体２１０４份血样进行了免疫球蛋白同种异型Ｇ２ｍ（２３）因子检测。经多元相关和多元回归分析发现，中国人Ｇ２ｍ（２３）基因频率分布呈沿海拔高度和纬度变化的渐变群。据此建立了可预测中国人群Ｇ２ｍ（２３）基因频率的多元回归方程。本文还讨论了Ｇ２ｍ（２３）基因频率形成渐变群的原因。
The distribution of G2m(23)gene frequencies in eight Chinese populations,which cover three ethnic groups, was studied by enzymelinked immunosorbent assay inhibition test. According to the results of multiple linear regression and multiple liner correlation there exists a cline of G2m(23)gene frequencies along with the height and latitude in China. In addition, an equation of multiple linear regression which can be used to expect the G2m(23)gene frequencies in some Chinese populations was established. Some possible reasons for this cline were also discussed.
基金
纽约中华医学基金
关键词
免疫球蛋白
同种异型
G2M
基因频率
免疫遗传学
Immunoglobulin allotype, G2m(23),Immunogenetics,Gene frequency,Cline, Multivariate analysis
