摘要
目的 探讨口腔阻断压 (p 0 .1)评估慢性阻塞性肺疾病 (COPD)患者生活质量、运动耐量、肺功能严重程度、血气等相关因素价值。方法 全部病例按GOLD分级标准分为 3组 :ⅡA级组、ⅡB级组、Ⅲ级组 ,测量所有患者呼吸驱动、肺功能、血气、生活质量问卷、6min步行距离。结果 Ⅲ级组COPD患者 p 0 .1%高于ⅡA级组和ⅡB级组 ,ⅡA级组和ⅡB级组比较无显著性差异。p 0 .1与 6min步行距离、症状、活动、影响、总分、FEV1、FEV1/FVC、最大吸气压占预计值的百分比 (Pimax% )、pH、p(CO2 )、FVC、PEF相关 ,与 p(O2 )、最大呼气压占预计值的百分比 (Pemax% )不相关。用逐步回归分析 ,FEV1、症状评分、6min步行距离、pH对p 0 .1有显著影响。应用支气管扩张药物后 ,p 0 .1有显著升高。结论 作为一种简单易行的无创检测方法 ,p 0 .1百分比评估COPD患者生活质量、活动能力、肺功能严重程度。
Objective It is to discuss the value of mouth occlusion pressure (p 0.1) on the life quality, exercise tolerance, severity of pulmonary function, arterial blood gases in chronic obstructive pulmonary disease (COPD) patients. Methods All the patients were divided into degree ⅡA group, degree ⅡB group, degree Ⅲ group according to COPD separate criteria. The respiratory drive, pulmonary function, blood gas and walk distance within 6 min of all patients were measured and the life quality questionnaire was done. Results p 0.1% of COPD patients in degree Ⅲ group was higher than that in degree ⅡA and ⅡB group, but there was no significant difference between degree ⅡA and ⅡB groups. p 0.1 had relationship with walk distance within 6 min, symptom, activity, influence, total score, FEV 1, FEV 1/FVC, Pi max%, pH, p(CO 2), FVC and PEF, and had no relationship with p(O 2) and Pe max%. FEV 1, symptom score, walk distance within 6 min and pH had significant influence on p 0.1 through stepwise regression analysis. p 0.1 increased significantly after bronchodilator was used. Conclusion As a kind of non-trauma and simple detection method, p 0.1 percentage has a good value to evaluate life quality, locomotor activity, severity of pulmonary function and blood gas.
出处
《现代中西医结合杂志》
CAS
2005年第8期993-994,998,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
呼吸驱动
肺功能
生活质量
6MIN步行距离
血气
respiratory drive
pulmonary function
life quality
walk distance within 6 min
blood gas
