摘要
合成了一些原卟啉肟同系物，它们的最大吸收波长为６７０ｎｍ，在肟衍生物的存在下，用红光照射２’，３＇－哑丙基鸟苷（ＩｐＧｕ）溶液，它们对ＩｐＧｕ的光分解作用比对照品血卟啉强约一倍。
Some oximic analogues of
protoporhyrin were prepared. They all show maximumabsorption at 670
nm,Illumination of 2’,3'- propylidene guanosine(IpGu )with a red
light in thepresence of oximic derivatives results in high
photodegradation of IpGu which is twice as large as thatof
haematoporphyrin(HP)。
出处
《药学学报》
CAS
CSCD
北大核心
1994年第3期180-184,共5页
Acta Pharmaceutica Sinica
关键词
原卟啉二甲酯
肟同系物
抗癌药
Cancer photedynamic therapy,2’,3'-
propylidene guanosine, Photoprotoporphyrindimethyl esters/Oximic
analogues
