摘要
目的:研究β-环糊精包合佛手、香附、木香混合挥发油的最佳工艺。方法:以挥发油包合率为评价指标,对饱和水溶液法、研磨法及超声法进行了比较试验,采用正交试验法,优选研磨法的最佳包合工艺条件,并对包合物进行TLC检验及稳定性考察。结果:优选出的最佳包合工艺条件是:β-环糊精与挥发油的投料比为 101,加 3倍量水,研磨 3h。混合挥发油包合前后,成分未见明显改变,包合后制剂的稳定性增强。结论:本实验为确认佛手、香附、木香混合挥发油的合理包合工艺提供了实验依据。
Objective: To study the best preparation of naphtha of Fuoshou and Xiangfu and Muxiang packed by β-CD. Method: To make the package rate of naphtha as the evaluating indicator; to make a comparative test with the method of saturated water solution, trituration method, and ultrasound method; to use orthogonal design and select the best packed preparation condition of trituration method, after that, to examine the packed substance with TLC and review its stability. Result: the best packed preparation condition based following conditions.β-CD : naphtha=101, adding 3 times water, tuiturating 3 hours. Before or after packing compound naphtha, its contents had not obvious change, after packing, the preparative stability was strengthened. Conclusion: The experience supplied experimental gist for affirming the correct packed preparation of compound naphtha of Fuoshou and Xiangfu and Muxiang.
出处
《中医药导报》
2005年第3期59-61,共3页
Guiding Journal of Traditional Chinese Medicine and Pharmacy
