摘要
目的 探讨更年期综合征女性血脂与血液流变学改变及其机制。方法 测定 110例更年期综合征妇女 (观察组) 和 100例健康妇女 (对照组) 的血脂、血液流变学共 15项指标。实验数据采用SPSS软件进行统计、t检验和相关性分析。结果 对照组与观察组的血清总胆固醇, 甘油三酯, 载脂蛋白A, 载脂蛋白B, 低、中、高剪切率全血粘度, 血浆粘度, 血沉, 血细胞比容, 血沉方程K值, 全血还原粘度, 红细胞聚集指数和红细胞刚性指数差异均存在显著性意义 (P<0 .05)。甘油三酯与高密度脂蛋白、高密度脂蛋白与载脂蛋白A呈显著相关(P<0 .05)。结论 更年期综合征患者具有明显血脂和血流改变, 治疗应着重降脂、稀释血液、改善微循环, 以减少动脉粥样硬化、血栓等疾病发生的危险。
Objective To investigate the changes and mechanism of blood lipid and hemorheology in women of climacteric syndrome.Methods We selected 110 climacteric women as experimental group and 100 health women as compared group.Determined 15 items of blood lipid and hemorheology,then analysed them with SPSS software.Results There're significant difference (P<0.05)in TC,TG,ApoA,ApoB,ηb(5.75s-1),ηb (30s-1),ηb(200s-1),ηp,ESR,Hct,ESRK,the whole blood reduction viscosity,aggregation index and deformation index of RBC between two groups.The correlations of TG and HDL,HDL and ApoA are obviously (P<0.05).Conclusion There're significant changes of blood lipid and hemorheology in women of climacteric syndrome.Reducing blood lipid,diluting blood and improving micro-circulation are the primary therapies to deduce arteriosclerosis and thrombosis of climacteric women...
关键词
更年期综合征
血脂
血液流变学
Climacteric syndrome
Blood lipid
Hemorheology
