摘要
【目的】探讨胆道梗阻解除后肝功能指标的变化。【方法】研究对象为54例胆道梗阻患者,所有患 者均行内镜下乳头括约肌切开(EST),根据病情予内镜下鼻胆管引流(ENBD)18例及内镜下胆管内引流 (ERBD)8例,测定术前及术后3～7d肝功能指标(TBIL、DBIL、ALT、ALP、PT)。【结果】①54例术后体温降 至正常,腹痛缓解,黄疸逐渐消退。②胆道梗阻术后3～7d,TBIL、DBIL、ALT、ALP均显著低于术前(P<0. 01),PT显著低于术前(P<0.05)。【结论】临床观察表明内镜下胆道梗阻解除后肝脏功能较快得到恢复,内 镜下EST、ENBD、ERBD是有效的胆道引流方法,一旦发生胆道梗阻应及时采取治疗解除梗阻,减轻对肝脏 的损伤。
ObjectiveTo explore the changes of liver function markers after relief of biliary obstruction by endoscopic treatment.Fifty-four patients,31 men and 23 women with biliary obstruction, were studied. The mean age was 54.3 years. All patients underwent endoscopic sphincterotomy (EST),eighteen patients also underwent endoscopic nosabiliary drainage(ENBD), eight patients underwent endoscopic retrograde biliary drainage(ERBD). Serum bilirubin, alanine transaminase (ALT),alkaline phosphatase (ALP) and prothrombin time (PT) were measured just before and 3rd^7th days after releasing from biliary obstruction.① The pain of all patients was relieved after endoscopic treatments. ② The levels of liver function markers (TBIL、DBIL、 ALT、ALP、PT) after relief of biliary obstruction decreased significantly.[Conclusion]Liver function markers recover quickly after relief of biliary obstruction in time. EST、ENBD、ERBD ware efficient methods to relieve biliary obstruction and promote the recovery of liver function.
出处
《医学临床研究》
CAS
2005年第2期161-162,165,共3页
Journal of Clinical Research
