摘要
对曾进行右心微导管检查并同步描记 LSTI,RSTI 的12例慢性支气管炎(简称慢支)和18例肺心病患者的 MPAP、DPAP、LPEP/LVET、ECG、胸部 X 光、血气检查资料、以及伴随的心血管疾患和左心功能障碍的病史及临床表现进行了回顾性对照研究。结果提示:肺心病(重症慢支组病人)左心功能损害发生率明显高于慢支组(轻症组)。其病理机制可能是多方面的。在重症慢支肺心病患者,低氧血症、高碳酸血症、感染、肺内分流等对左心室损害,以及右室肥大对左室顺应性的影响,可能是促成肺心病并发左心功能障碍的重要因素,而某些高龄肺心病患者并存的心血管疾患可能是肺心病病人存在左心功能障碍的主要原因。
The data obtained from 12 cases of COPD and 28 cases of cor pulmonale with the examination of right-cardiac microcatheterization were analyzed retrospectively.The average pulmonary arterial pressure,end-diastolic pulmonary arterial pressureand systolic time interval of the left ventricle through the records of ECG,phono- cardiogram and carotic pulsegram was studied simultaneously.ECG,chest X-ray andblood gas analysis as well as the history of cardiovascular disease and left heartdysfunction were also investigated on two groups of patients.The result revealedthat the incidence of left heart dysfunction in the group of cor-pulmonale washigher significantly than that in the group of COPD.The pathological mechanism ofcomplicated left heart dysfunction might include myocardia damage resulting fromanoxemia hypercapnia and severe infection as well as disturbance of the right ven-tricle for compliance of the left ventricle in severe cor-pulmonale and complicatedcardiovascular disease might be important factrs in the development of left heart dysfunction in aged cor-pulmonary patients.
出处
《天津医药》
CAS
1989年第9期515-519,共5页
Tianjin Medical Journal
