摘要
本文采用熔融法制得了氨苄青霉素栓剂,对其进行了质量考察及体外溶出的研究。结果表明,以半合成脂肪酸酯为基质制得的栓剂,加入适量吐温80能显著提高氨苄的体外溶出。
mpicillin suppository was prepared with melting
method and itsqualities and dissolution were studied.It was found that
the dissolutionrate can be increased significantly by ad ding Tween 80.
关键词
氨苄青霉素
累积溶出
栓剂
药剂学
Ampicillin
cumulative dissolution
percentage
suppository
polysorbates