摘要
本文采用损伤家兔眼浅层角膜、感染金葡菌或绿脓杆菌，造成金葡菌和绿脓杆菌性角膜炎动物模型。采用环丙沙星滴眼液治疗，并分别与利福平和丁胺卡那霉素滴眼液比较。结果表明：环丙沙星滴眼液对金葡肉和绿脓杆菌性角膜炎有显著的治疗效果，其作用较利福平和丁胺卡那霉素滴眼液快而强，并能有效地预防角膜溃疡的形成。提示：国产环丙沙星滴眼液可作为治疗细菌性角膜炎的有效药物。
Animal models of Staphylococcus Aureus and Pseudomonas Aeruginosa Keratitis were established by injuring the superficial cornea of rabbit eyes,and then infecting it with Staphylococcus Aureus or Pseudomonas Aeruginosa.The animal models were treated by ciprofloxacin eyedrop.The therapeutic action for cipronoxacin eyedrop was compared with that for rifampin and amikacin eyedrop respectively. The results showed that ciprofloxacin eyedrop had a remarkable therapeutic effect for two kinds of keratitis, and it was quicker and stronger than rifampin and amikacin eyedrop. Ciprofloxacin eyedrop could also effectively prevent the formation or Corneal ulcer.
出处
《南通医学院学报》
1994年第2期148-150,共3页
ACTA Academiae Medicinae Nantong
关键词
细菌性
角膜炎
环丙沙星
滴眼液
staphylococcus aureus keratitis
pseudomonas aeruginosa keratitis
ciprofloxacin eyedrop
therapeutic effect
