摘要
用硫氰酸钾与硫代磷酰氯制备了硫代磷酰异硫氰基酯和二异硫氰基酯，并以其与不同胺反应，合成了硫代磷酰取代硫脲和硫代磷酰－双－取代硫脲两系列２０个新的有机磷化合物。经＾１Ｈ ＮＭＲ、１Ｒ及元素分析确定了它们的化学结构，测定了它们的生物活性。结果表明只有Ｏ－异丙基，Ｏ－（４－甲基－２－硝基苯基）－Ｎ＇－萘基硫代磷酰硫脲（ＰＤ－１）具有较好的杀菌活性。
From thiopliosphorylchloride and potassium thiocyanate,series of phosphoro(isothiocyanatido)thioates and phosphoro-bis(isothiocyanatido)thioates were prepared,andthen through the reactions of these componds with amines two series of new oganic phosphorus compounds(RO)(ArO)P(S)NHC(S)NR￣1R￣2 and(RO)P(S)[NHC(S)NR￣1R￣2]_2 were prepared.The structures of these compounds have been confirmed by IR, NMR, and elementary analysis.The results from the preliminary bioassay showed that compound PD-1 has fairlygood bactericidal activity.
出处
《高等学校化学学报》
CSCD
北大核心
1994年第11期1634-1638,共5页
Chemical Journal of Chinese Universities
基金
辽宁省教育委员会重点学科基金
关键词
氧-烷基
取代硫脲
杀菌活性
驱虫剂
动物
O-alkyl
O-arylphospl1oro(thioureido)thioates
O-alkylphosphoro-bis-(thioureido)thioates
Bactericidal activity
