摘要
于１９９０～１９９２年对中国东部的徐州地区８５５４７名居民进行了地方性甲状腺肿的调查和环境碘的监测。显示徐州地区存在甲状腺肿（肿大率５．６％～５４．４％，患病率０．３％～８．８％），以Ⅰ度肿大和弥漫型为主（构成比分别为９５．０％和９８．７％）。女性发病高于男性；年龄人布以１０～１９岁组为高发组段；地理分布呈以徐州为中心的同心园分布，中心低，周边高。进一步研究还发现，在低碘地区（平均饮用水碘１０．８μｇ／Ｌ，平均尿碘５３．０μｇ／ｇ·Ｃｒ），地甲病患病率和碘含量（水碘和尿碘均呈负相关关系（ｒ１＝－０．８９５，Ｐ１＜０．０５；ｒ２＝－０．９０１，Ｐ２＜０．０５）。在高碘区（平均饮用水碘２８７．３μｇ／Ｌ，平均尿碘２８５．３μｇ／ｇ·Ｃｒ），地甲病和碘含量无相关性，可能有其他致病因素，有待进一步研究。本次调查样本量较大，为全面了解中国东部的徐州地区地甲病流行情况和制订防治措施建立了本底资料。
n 1990～1992 year,we conducted a relatively large scale investigation of endemic goiter in Xuzhou ar-eas. A total of 85 547 residents had received a check─up and the environmental iodines were surveided. Theresults showed that Xuzhou area is a low epidemic area of endemic goiter(goiter enlargement rate 5.6%～54.4%,prevalent rate 0.3%～8.8%). Female has much higher prevalence than male and the persons of 10～19 teay of age also hav higher prevalence as well.In geographical distribution,the goiter prevalence in Xuzhoucity is lower than that of counties around Xuzhou city. With further studies,we found endemic goiter and io-dine content in water and urine assumed negative correlation(r1=─0.895,P1<0.05;r2=─0.901,P2<0.05)in lower iodine content area(average water-iodine 10.8μg/L,average urinoiodine 53.0μg/g. Cr and no corre-lation in higher iodine content area(average water─iodine 287.3μg/L,average urino-iodine 285.3μg/g.Cr ).With this relatively large scale investigation,we understand the epidemic status of endemic goiter inXuzhou areas and can work out the prophylaxis and treatment measures of endemic goiter.
出处
《地方病通报》
1994年第1期58-61,共4页
Endemic Diseases Bulletin
关键词
地方性
甲状腺肿
患病率
水碘
尿碘
Endemic goiter
Goiter enlargement rate
Water─iodine
urino─iodine
Xuzhou areas
