摘要
为了探讨胆汁中胆固醇和胆红素共同沉淀成石的规律,本文对胆汁中胆固醇和胆红素含量进行相关性分析。观察胆红素的参数为:总胆红素量(TB)、直接胆红素量(CB)、游离胆红素量(UCB)和游离胆红素百分比(UCB％);而观察胆固醇系的参数为:胆固醇量(Ch)、磷脂量(PL)、总胆盐量(BS)及成石指数(LI)。结果在组间对照研究中发现致石胆汁(70例)中UCB％和LI呈明显负相关,而非致石胆汁(8例)中无此现象。在同组对照研究申发现,当致石胆汁逆转为非致石胆汁后,UCB％和LI间原存的负相关关系随之消失。作者提出“空格占位“论对此作出解释。
In order to explore the required common conditions for the precipitation of cholesterol and bilirubin in bile and for gall-stone formation, we studied the correlation between the concentrations of these substances in bile. Amount of TB, CB, UCB and UCB% were chosen to represent bilirubin content, and Ch, PL, BS and LI for the cholesterol system. The result of intergroup control study showed that there was a negative correlation between LI and UCB% in 70 specimens of non-lithogenic bile, while non-correlation in 8 specimens of non-lithogenic bile. The result of intragroup control study showed that the negative correlation between LI and UCB% disappeared when the lithogenic bile was reversed into non-lithogenic bile. The hypothesis of 'space-occupation' was put forward by the authors to explain the phenomena.
出处
《上海医学》
CAS
CSCD
北大核心
1989年第12期709-712,共4页
Shanghai Medical Journal
