摘要
目的比较不同分割放射治疗骨转移癌患者的时间效应，评价不同分割放疗的止病疗效。材料与方法对1992年5月～1997年5月我院收治的123例骨转移癌患者分别给予常规分割组、超分割组及大剂量低分割组不同的放射治疗，观察各组姑息止痛的放疗有效率．结果放疗1周时，止痛有效率为5．41％、10．3％及65．2％；放疗结束时为70．3％、77．3％与77．3％；放疗结束后3个月为65．0％、67．6％及74．2％．经统计学分析发现放疗1周时大剂量低分割组止痛有效率与其它组比较有明显差异。结论大剂量低分割放疗止痛率高，疗效出现早，而放疗结束时及结束后3月3组止病率无差异。故在骨转移癌的放疗中可考虑采用先大剂量低分割放疗后继常规或超分割的放疗方式。
Purpose To evaluate the time - response and effect of different fraction radiotherapy in the treatinent ofmatastatic bone pain. Methods one hundred and twenty-three cases of painful bone metastases received different fraction radiotherapy 4uring May 1992 to May 1997 in our hospital. Results The relieving pain rate of regular fractionat-ed,hyperfractionated and the large dose and low fractionated radiotherapy were 5. 41%, 10. 3 % and 65. 2 % respective-ly at the time of a week later during the therapy. After radiotherapy and three months later the rate were 70. 3%,70. 0%, 73. 3% and 67. 6%, 74. 2 %, 65. 0%- The difference of low fractionated radiotherapy was significant. Conclu-sious The efficacy of low fraction was high and in short time. After radiotherapy and three months later the rate wasinsignificant. lt showed that the efficacy of low fractionated is better than that of others in the treatment of metastaticbone pain. We can give the low fractionated radiotherapy 10 Gy at first,then hyperfractionated or regular fractionatedto 40 Gy in the treatment of metastatic bone pain
出处
《华北煤炭医学院学报》
1999年第6期505-506,共2页
Journal of North China Coal Medical College
关键词
骨转移癌
放射治疗
分割
metastatic bone cancer radiotherapy fractionation
